However, the Vitiligo Surgical Treatments always take part only when topical steroids or PUVA therapy fails to repigment, Vitiligo Surgical Treatments may be undertaken. Vitiligo Surgical therapies are time-consuming and can be considered in inactive, non-progressive disease only. They are best suited for segmental and localized vitiligo. Areas such as fingers, ankles, forehead and hairlines tend to show poor results.
Autologous minigrafting. Multiple, small punch biopsy specimens are taken from an appropriate donor site and at the recipient treatment site where the biopsy sites are separated by 4 to 5mm of vitiliginous skin. The donor specimens are placed on the recipient defects and the grafts are sealed. Centrifugal pigmentation spreads from the recipient site. Concomitant PUVA therapy may help pigment spread. This procedure may give excellent results in segmental vitiligo. A cobblestone appearance or scarring may occur at the treatment site.
Epidermal grafting involves formation of blisters at the donor and recipient sites by the use of a suction apparatus and removing the roof of the blisters. The roof of the blisters of the donor sites are placed on the denuded areas on the recipient sites and dressings are applied on the donor as well as the recipient sites.
Transplantation of in vitro-cultured melanocytes on denuded areas of vitiliginous recipient sites has also been successful in producing cosmetically acceptable repigmentation of vitiligo.
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