New Effective Vitiligo Treatments

New Effective Vitiligo Treatments What is Vitiligo? Vitiligo affects one person of 200 peoples. Skin cells that produce a pigment known as melanin. Vitiligo occurs when melanin cells keep dying or not in a proper condition. The skin is removed from pigment, so that traces of bodies which excel especially in the types of dark skin. It is rare that the pigment to return back to normal. The cause is unclear, but the impairment could be inherited in some patients, or possibly to a weakened immune system related.

All treatments new vitiligo treatments are not promise to cure the vitiligo. Most vitiligo cases are affected relatively small areas of the skin and the standard vitiligo treatment is to conceal the use of cosmetic creams. Sunscreens are important for the prevention of sunburn to affected areas, and advice to vitiligo victims who come with their state aid.





Medical popular vitiligo treatment is difficult and often not completely effective. Topical PUVA (psoralen and ultraviolet A therapy) is for the patient psoralen, which makes your skin sensitive to light type. It is up to the skin or orally, then the patient is exposed to ultraviolet light. vitiligo treatment must be repeated several times to achieve repigmentation to be continued in part, and usually have six to 18 months.

There are two major potential side effects of PUVA to a vitiligo patients: severe burns and blisters and excessive darkening of the treated patches on the skin or normal environment vitiligo] [hyperpigmentation. Usually disappear when treatment is over. Known side effects of oral psoralen sunburn, nausea and vomiting, itching, abnormal hair growth and hyperpigmentation. Oral PUVA may increase the risk of skin cancer, so patients should apply sunscreen and avoid direct sunlight for 24-48 hours after each treatment and UV protective goggles 18 to 24 hours after each treatment to avoid eye injuries, especially cataracts.

vitiligo patients whose the disease affects more than 50 percent of his body, sometimes the doctor depigmentation by the application of a drug for normal skin, the color corresponds to the areas affected vitiligo. The results are permanent and irreversible. In addition, by submitting to the depigmentation of the person always abnormally sensitive to sunlight.

All surgical treatments such as skin grafts, should be considered experimental because their effectiveness and side effects are not yet fully defined.

In 1963, scientists from the National Institute of Mental Health, United States, noted that tetrahydrobiopterin is a small natural molecule, an essential coenzyme. This means that participates in chemical reactions at the site in order to accelerate the reaction. Over the past decade, other scientists have a treatment that would allow the pigmentation to be changed naturally developed. They found that tetrahydrobiopterin developed factor for discoloration and pseudocatalase cream on the basis of his discovery to cure vitiligo.

In a pilot study in 1990, 33 patients with vitiligo have been successful with current pseudocatalase, calcium, and deals with a short-term exposure to UVB light. Initial vitiligo repigmentation occurred in most cases within 2-4 months. Complete vitiligo repigmentation was achieved with a rate of 90 per cent success in the faces and hands have been affected. In all patients, active depigmentation was arrested. None of them developed new lesions during treatment. No recurrence was observed during two years of monitoring.

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New Vitiligo Cure - with Black Pepper

New Vitiligo Cure - with Black Pepper Black pepper promises cure for vitiligo

This is new invention for a vitiligo treatment? Just read the news below, surely a new hope for vitiligo patient.

LONDON, Feb 14 (Reuters) - Black pepper could lead to better treatments for skin disease that affects the disfigurement of about 1 percent of the world's population, British researchers on Thursday.
A team from King's College London showed in a study of mice that Piperine - the compound that gives black pepper, spicy, pungent flavor - and its synthetic derivatives helped stimulate pigmentation in the skin of people with vitiligo.

Piperine was particularly effective when combined with photo-therapy treatment with UV radiation, researchers in a study to be published in the British Journal of Dermatology.



"We have shown that topical treatment with Piperine stimulates even pigmentation in the skin," Anthony Young, a photo-biologist at King's College, who worked on the study, said in a statement.

"This provides support for future clinical evaluation of Piperine and its derivatives as novel treatments for vitiligo.

The disease, which pop star Michael Jackson in the past attributed his gradual skin whitening, destroys the melanin which gives skin its color. Melanin protects from ultraviolet rays so victims run a much higher risk of skin cancer.

Vitiligo is of particular concern in people with darker skin, the researchers said.

Current vitiligo treatments include steroids applied to patchy skin and photo-therapy. But many people do not respond to hormones and the photo-therapy may increase the risk of skin cancer, researchers said.

The team compared the effects of Piperine and its derivatives when applied to the skin of mice, either alone or followed by radiotherapy.
They found that when used only in the compounds stimulated pigmentation, light brown over a period of six weeks. When boosted by radiation, the vitiligo treatment led to even darker skin in the same period of time.

New Vitiligo Cure - with Black Pepper copyright vitiligo treatments

Vitiligo Surgical

Surgical Techniques for Vitiligo: A Review
N. van Geel, K. Ongenae, J.-M. Naeyaert

Although the treatment of vitiligo has improved during the last decade, therapy is still not satisfying for many patients. This is probably due to the fact that the aetiopathogenesis is unknown. Several vitiligo treatment modalities, such as PUVA, UVB and local corticosteroids are currently used in the treatment of active vitiligo. However, these treatments usually induce incomplete repigmentation. Surgical vitiligo methods intended to repigment leucoderma are an interesting therapeutic option if patients have stable disease. Two types of surgical techniques are available: tissue grafts and cellular grafts, with in between autologous cultured epithelial grafts. Tissue grafts are full-thickness punch grafts, split-thickness grafts and suction blister grafts. With tissue grafts, only a limited surface area can be treated but with good results in the majority of cases. Cellular grafts include non-cultured keratinocytes/melanocytes and cultured melanocytes. The exact success rate of repigmentation with cellular grafts is still unknown, since only a small number of studies have been published. Starting from autologous cellular suspensions, epithelial grafts of various compositions can be cultured in vitro. They can be used for larger areas. The purpose of this review is to describe the applications of different vitiligo surgical techniques used to treat recalcitrant vitiligo.

Copyright © 2001 S. Karger AG, Basel


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Author Contacts

J.-M. Naeyaert, MD, PhD
Department of Dermatology
Ghent University Hospital
De Pintelaan 185, B-9000 Ghent (Belgium)
Tel. +32 9 2402298, Fax +32 9 2404996, E-Mail jeanmarie.naeyaert@rug.ac.be

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SURGICAL TECHNIQUES FOR VITILIGO : A Review

Vitiligo treatments - new vitiligo cure method using Tacrolimus

Tacrolimus was as effective in the treatment of vitiligo Clobetasol and how can the best first-line treatment for sensitive skin areas, according to the results of a randomized, double-blind study published in the May issue of Archives of Dermatology.

The hypothesis was that its immunomodulatory properties and safety profile of corticosteroids, tacrolimus ointment may be a better benefit-toxicity ratio and a new therapeutic alternative to topical corticosteroids in children with vitiligo, known that from experience that corticoids Clobetasol is more effective for vitiligo, the pigment often than other topical steroids have failed. That is why they decided instead Clobetasol propionate midpotency other steroids for this study.



The 20 children in this study had untreated vitiligo with topical or systemic more than two months before the study. In each child, two symmetrical lesions of about the size and development time was treated with topical tacrolimus 0.1% and the other with 0.05% Clobetasol propionate two months.

Of the 20 patients, 18 (90%) experienced some repigmentation in digital morphometry, Clobetasol repigmentation of 49.3% and 41.3% for tacrolimus. Adverse events were atrophy and telangiectasia three lesions in two lesions with Clobetasol and a burning sensation in two lesions with tacrolimus.

Tacrolimus is almost as effective as Clobetasol propionate to restore skin color in lesions of vitiligo in children. "Because there was no atrophy or other adverse effects, tacrolimus may be useful for younger patients and for sensitive areas of skin such as eyelids, and must be taken into account other skin disorders currently treated with topical steroids for a long time. It would be interesting to see whether longer periods of treatment, the combination of tacrolimus with other topical agents, or elevated concentrations of tacrolimus can lead to better results than the ones in this series and whether the negative results in Acral can be overwritten with each of these approaches.

In an accompanying editorial, Heidi Plettenberg, MD, to Assmann, MD, and Thomas Ruzicka, MD, of Heinrich-Heine University in Dusseldorf, Germany, considering the photo-therapy and other options for the treatment of vitiligo last. Suggest that tacrolimus is usually more effective in head and neck injuries, and suggest that the low response rate in this study were the limited duration of therapy.

The current data suggest that tacrolimus may represent ... a new option for "vitiligo effective treatment" of childhood vitiligo, with the appropriate use and limited adverse effects," they write. "The efficacy of this immunomodulatory drug provides new evidence for the hypothesis of self-destruction of melanocytes in vitiligo.

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HOW TO CURE VITILIGO

Vitiligo - how to cure it. The medical term for white spots on the skin or Leukoderma Vitiligo. It is a disease of the skin, the skin loses its color by some genetic causes or environmental problems. The white spots appear as white patches of skin without pigment which called Vitiligo.

White spots on the skin are common in people with autoimmune diseases. One of these diseases is the lack of adrenal cortex. The adrenal glands is responsible for the production of a hormone called corticosteroids. The disease occurs when a shortage of this hormone in the body. For this reason, the common treatment as suggested by the doctors for vitiligo is corticosteroid cream.



Another treatment in the treatment of white patches on the skin in the sun for a long time or artificial light. The cells are responsible for the pigmentation is activated when the skin is exposed to light.

Melanocytes, the cells of the skin caused pigmentation. A recent progress in medicine, the transplantation of cells from another part of the body from the skin achieved. Following the transplant Vitiligo, or white patches on the skin can be completely cured.

Cosmetics can also be used to conceal the white spots or Vitiligo. The Vitiligo treatments should be used to combat the disease, because they can education and uncontrollable. You must also know that this disease is hereditary, it can not be avoided. For this reason, a good and effective treatment is necessary to cope with the psychological pressure, harassment and frustration.

There are other conditions for the skin or diseases in which the skin loses its color and becomes darker or lighter shade. Before using any of the treatments for Vitiligois better, a dermatologist and the symptoms to be confirmed.

In most cases, only the current treatments are provided by doctors for the skin with Vitiligo, acne and eczema. In some oral contraceptives May also be required if the situation is serious.

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